Bupivacaine
2-5% Lidocaine 2-10% NMDA Ca channel antagonist Ketamine 5-10% Amantadine 5-20% Dextromethorpan 5-10% Orphenadrine 5-10% Haloperidol 0.5-2% Glutamate antagonist Gabapentin 5-10% AMPA (Na+ channel) Gabapentin 5-10% Carbamazepine 5% Phenytoin 2-10% Valporic Acid 2-5% a2-Agonist Clonidine 0.1-0.3% NE reuptake inhibitors Tricyclic antidepressants a1-Antagonist Prazosin Phentolamine GABA b Agonist Baclofen NON-NMDA Ca2 + Channel blocker Nifedipine Opioids Morphine
1-5% Hydrocodone 0.25-1% Fentanyl 100mcg/0.1 ml
Sample of Transdermal Pain Medication Prescription Application
Medications
Options
Anesthetics
Rx Ketoprofen 20%__30%__40%__ 50%*__
Or Other NSAID in strength of choice or in different combinations
Diclofenac 1-10%
Ibuprofen 10-40%
Indomethocin 10-20%
Piroxicam 0.5-2%
Rx Guaifenesin 10 - 40%
Alone or in combination with NSAID for muscle sprains,
plantar fasiitis, and nocturnal leg cramps.
Normal Base used VPC
(Vanishing Penetrating Cream) (onset 15-30 minutes)
Anhydrous
PGE For trigger point Low strengths Lipoderm
High Strength Expensive Non-Sticky PLO Effective Sticky Under Dentures VPC High
Strengths Non-Sticky Cost
effective Speed
Gel Liquid (for ears) Runny Spray Sensitive Skin Can Run Considering the barriers to effective pain management
shared by patients and providers, it is time to consider a new approach for
the twenty first century. Using
low-dose concomitant agents with complementary modes of action can minimize
the problem of side effects. Also
knowledge of receptor locations to avoid oral or infusion systemic doses
when it become necessary to decrease the risk of side effects.
Base Options
Base Advantages Disadvantage
A New Approach
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